United States securities and exchange commission logo November 10, 2021 Ravi Tulsyan Chief Financial Officer XPO Logistics, Inc. Five American Lane Greenwich, CT 06831 Re: XPO Logistics, Inc. Form 10-K for the Fiscal Year Ended December 31, 2020 Filed February 12, 2021 File No. 001-32172 Dear Mr. Tulsyan: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Energy & Transportation